Global R&D Senior Research Chemist - Metabolism and Pharmacokinetics

Department:  Research and Development
Date:  May 22, 2023

FMC Corporation is a global agricultural sciences company dedicated to helping growers produce food, feed, fiber and fuel for an expanding world population while adapting to a changing environment. FMC's innovative crop protection solutions – including biologicals, crop nutrition, digital and precision agriculture – enable growers, crop advisers and turf and pest management professionals to address their toughest challenges economically while protecting the environment. With approximately 6,400 employees at more than 100 sites worldwide, FMC is committed to discovering new herbicide, insecticide and fungicide active ingredients, product formulations and pioneering technologies that are consistently better for the planet.

 

FMC is a globally diverse organization that offers its employees exciting opportunities to work on challenging projects that are important to the achievement of our strategic objectives.  With a corporate culture of innovation, integrity, responsibility and customer intimacy, we foster “The Right Chemistry” in everything we do. We are looking for people to join us in creating, developing, and improving our products, our processes, and our markets. If you are ready to make a difference every day, FMC is ready to talk to you.  Visit FMC to learn more and follow us on LinkedIn and Twitter

 

FMC’s Global Research and Development organization is looking for a highly-motivated individual to work in the Investigative Sciences Group at its Newark, Delaware, research facility. The successful candidate will support plant and animal metabolism and mammalian pharmacokinetic/toxicokinetic studies, including metabolite identification and physiology-based pharmacokinetic modeling.  Working in an interdisciplinary team environment, the successful candidate will form close partnerships with other scientists, communicating investigational results and placing them into context. The successful candidate’s responsibilities may also include fostering the development of associate scientists in this area.

 

Responsibilities

  • Function as a study monitor in the design, execution and interpretation of in vitro and in vivo ADME studies, mammalian pharmacokinetic/toxicokinetic, and plant and livestock metabolism studies placed at Contract Research Organizations.
  • Develop and/or make recommendations for analytical methods for studies including metabolite identification from plant and animal metabolism studies and help ensure that technical procedures used for testing and research are current and valid.
  • Execute in-house in vitro and in vivo animal and plant metabolism studies, perform metabolite structure elucidation, pharmacokinetic data analyses and physiology-based pharmacokinetic (PBPK) modeling
  • Review all experimental data and ensure timely delivery of analytical reports that may be used for decision-making. Interpret and report the results of experimentation using effective communication skills.
  • Maintain knowledge of regulatory and compliance requirements.
  • Demonstrate leadership qualities that set a high standard for interpersonal interactions, organizational skills, initiative, team spirit, conflict resolution, decision-making and work ethic.
  • Thrive in an environment where work involves colleagues from multiple disciplines in a matrixed environment.
  • Interact with regulatory agencies to address concerns with products currently in development or marketed products.
  • Participate in industry task forces and/or Agency meetings to keep abreast of new developments in the areas of PBPK.
  • Advance FMC core values, e.g., safety, respect, environmental stewardship and ethics.

 

Required Education

  • A Ph.D. degree in Analytical Chemistry, Biochemistry, Pharmacology or a related discipline with 5 or more years of experience or a M.S./B.S. degree in Analytical Chemistry, Biochemistry, Pharmacology or a related discipline with 10 or more years of experience.

 

Qualifications

  • Practical experience of pharmacokinetics, pharmacodynamics, toxicology, metabolism, metabolite identification and structure activity relationships.
  • Strong chromatography and LC/MS skills for quantitation and structure elucidation.
  • Computer skills to quickly learn and evaluate new software and modify or trouble-shoot existing PBPK tools.
  • Experience working with radio-labeled materials.
  • Strong interpersonal skills including networking ability with the desire to contribute towards team success.
  • Excellent oral and written communication skills.
  • Excellent project management skills.
  • Demonstrated ability to work in a flexible environment, learning new skills which can be utilized across technical disciplines.   
  • Familiarity with PBPK modeling software such as Gastro Plus, SimCyp and/or WinNonlin or similar software.
  • Familiarity with global pesticide registration guidelines and data requirements, especially for ADME studies.

 

At FMC, diversity and inclusion are in our DNA. We are proud to be an Equal Opportunity Employer with a commitment to creating an inclusive workplace where all employees can thrive – regardless of race, gender, sex, pregnancy, gender identity and/or expression, sexual orientation, national origin or ancestry, citizenship status, color, age, religion or religious creed, physical or mental disability, medical condition, genetic information, marital status, military or veteran status, or any other basis protected by federal, state or local law. FMC also supports employee participation in company employee resource groups that celebrate the diverse backgrounds of our workforce by providing communities for employees to connect with each other and raise awareness throughout FMC. FMC complies with federal and state disability laws and makes reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, please contact our Talent Acquisition department


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