Metabolism Scientist

Department:  Research and Development
Date:  Nov 19, 2021

FMC Corporation is a leading specialty company focused on agricultural technologies. FMC provides innovative and cost-effective solutions to enhance crop yield and quality by controlling a broad spectrum of insects, weeds and disease, as well as in non-agricultural markets for pest control. FMC is a globally diverse organization that offers its employees exciting opportunities to work on challenging projects that are important to the achievement of our strategic objectives. Your education and professional experience are valued and put to use from day one. Your success at completing key initiatives can result in a varied, progressive and fulfilling career with FMC. With a corporate culture of innovation, integrity, responsibility and customer intimacy, we foster “The Right Chemistry” in everything we do. We are looking for people to join us in creating, developing, and improving our products, our processes, and our markets.  If you are ready to make a difference every day, FMC is ready to talk to you.

 

FMC Global Regulatory Sciences organization is seeking a highly-motivated individual to work in our Human Health Sciences Group at our Newark, Delaware, research facility. The Metabolism Scientist position requires broad knowledge of organic and analytical chemistry, radiochemistry, biochemistry and/or pharmacology with practical experience with pharmacokinetics, pharmacodynamics, and metabolism. This is an office-based position that utilizes experimental knowledge and regulatory know-how to support and advise internal multidisciplinary teams from early research and development through commercialization and registration of materials in the FMC agrochemical portfolio. This position supports internal scientists from aligned disciplines, such as toxicology, field residue, analytical chemistry, and risk assessment to make informed decisions about overall safety and risks and the ability to register active ingredients and agrochemical products. This position reports to the Manager of Metabolism and Residue.

 

Job Overview and Primary Responsibilities

  • Design, execute and interpret in vitro and in vivo metabolism studies at Contract Research Organizations.
  • Determine metabolic pathways and identify metabolites of agricultural active ingredients in various plant and animal matrices.
  • Plan and oversee the research of contract laboratories for metabolism studies to meet regulatory requirements.
  • Ensure all contract laboratory operations and record-keeping are of high quality and compliant with the GLP standards.
  • Review and summarize metabolism data from studies, literature, and other sources to prepare documents for submission.
  • Prepare written reports and oral presentations for product registration teams and regulatory agencies.
  • Prepare responses to regulatory questions in support of registration, renewal, and label expansion for products.
  • Effectively manage numerous tasks/projects simultaneously to meet internal/external deadlines.
  • Advance FMC core values of Safety, Respect, Stewardship, and Ethics.

 

Qualifications

  • Broad scientific knowledge in organic chemistry, analytical chemistry, pharmacology, metabolism, pharmacokinetics or similar scientific discipline related to agricultural or pharmaceutical products.
  • Ability to design and manage appropriate ADME, plant and livestock animal metabolism studies under regulatory guidelines. Familiarity with the isolation and structural identification of metabolites and degradants from biological systems using radiochemical and spectroscopic techniques.
  • Project management skills to monitor, manage, and meet deadlines for GLP-compliant studies conducted through external contract facilities.  
  • Excellent and effective written and verbal communication skills.  Technical writing capability for comprehensive scientific reports and presenting results to/for appropriate target audiences.  

Additional Beneficial Experience:

  • Registration support for agrochemical, pharmaceutical, or specialty chemicals.
  • Experience in preparing metabolism dossiers, scientific justifications/rationales for study waivers and overviews for registration submissions.
  • Participation in scientific societies, associations, and task forces.

 

Education

  • PhD in Chemistry, Biochemistry, Pharmacology, Medicinal Chemistry, Pharmaceutical Sciences or related discipline and a minimum 2+ years of relevant work experience in a commercial setting relevant to the pharmacokinetics and metabolism of organic chemicals.  
  • Or, MS in Chemistry, Biochemistry, Pharmacology, Medicinal Chemistry, or related discipline and a minimum 5+ years of relevant experience.

 

At FMC, diversity and inclusion are in our DNA. We are proud to be an Equal Opportunity Employer with a commitment to creating an inclusive workplace where all employees can thrive – regardless of race, gender, sex, pregnancy, gender identity and/or expression, sexual orientation, national origin or ancestry, citizenship status, color, age, religion or religious creed, physical or mental disability, medical condition, genetic information, marital status, military or veteran status, or any other basis protected by federal, state or local law. FMC also supports employee participation in company employee resource groups that celebrate the diverse backgrounds of our workforce by providing communities for employees to connect with each other and raise awareness throughout FMC.  FMC complies with federal and state disability laws and makes reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, please contact our Talent Acquisition department at talentacquisition@fmc.com.


Nearest Major Market: Philadelphia